From.Dr.junko

2018年10月23日
Novel SLE treatmentーHydroxy chloroquine

Beyond disease activity~Multiethnic longitudinal cohort (n=635)~
reduced damage accrual
decrease in renal damage
decrease in skin-damage
decrease in vascular events.
Anti-malarial toxicity
Rertina-weight based dosing:Toxicity near 1% after 5-7years:Cumulative dose of 1000g :Baseline then annual after 5 yrs.
Skin-Hyperpigmentation
Muscle-Curvilinear bodies:muscle fiber atrophy:Vacuolar changes
Toxic-Myocardial Disease:47cases median doses 1050g for CQ and 1542g for HCQ Chronic heart failure.
Excreted by kidney
High risk patients-concomitant tamoxifen(increase risk 5-fold)
GFR<50cc/min, dose>5mg/kg
Risk is <2% up to 10 yrs but rises to 20 % after 20 years.
safe rule is 5x5 Screen after 5 yrs use and <5mg/kg real weight
[picture: a sunday on La Grande Jatte]

2018年10月21日
AmericanCollege of Rheumatology in Chicago

I started checking “Lupus nephritis”.

Here is Dr. Igawa, who worked for us lang time ago and He worked catheterization in Shimonoseki, does the research in Nagasaki Univ. about Lupus nephritis. He investigated the
Cause of Lupus nephritis.

Good Job! Dr. Igawa

2018年10月20日
American College of Rheumatology in Chicago

CHICAGO, CHICAGO!!!
fantastic!!!

Ooops,
We can see "TRUMP TOWER!".
Let's see ......go back to meeting and study!

2018年10月06日
10th anniversary in Kawata-Junko Clinic

Thanks you for 10 years anniversary in Kawata-Junko clinic.
We came lomg way.
Human-being are social creature.
I felt strange power for ten years.

2018年10月06日
lecture ofconnective tissure diseases in Kaiko Messe in Shimonoseki

We had typhoon today.
I did that during the storm.
Thank you for coming.

I talked about Nobel prize winner,Yamaguchi-native DR. Honsyo,
What he had done , and immunology.

We are planing to have it next end of March.
Thanks,

2018年09月21日
Academic meeting for radiological technologists

There are meeting for radiological technologists.
Over 2000 people crowded into the bar and pubs.

2018年09月11日
Dr. Mart Mannik

Mart Mannik M.D., Professor, Head of division of Rheumatology in Univ. of Washington from 1967-2001 passed away on Wed. August 22th in 2018 at the age of 86. Refugee of WW II born in Estonia. Received M.D. in Cleveland OHIO, Residency training in MGH. Mannik had long career in UW rheumatology.
He played commanding role in shaping Rheumatology in Pacific Northwest in U.S.A. He was P.I.(Primary investigator), he supervised 100 rheumatologist. Dr. Mannik helped to transform this region of the Country from Low awareness and skills in Rheumatologic disorders to a stronghold of high quality clinical care and outstanding basic rheumatologic investigation.



2018年09月07日
Meeting of peripheral neuron in Shimonoseki

The meeting of Peripheral neuron was held in Shimonoseki,
Kaiyo messe.
Prof. TAKASHI KANDA serves as a host of this meeting.

Autumn is The seasons for meeting.

2018年09月03日
female bathroom

Any bathroom women can use.
We have one more bathroom upstairs, so you can offer.

In general women need bathroom three time more often than men.

2018年09月01日
General practice conference in Shimonoseki

…。